Scientist Bruce Banner has been living in the shadows, scouring the earth for an antidote to his curse of turning into the Hulk when he becomes angry and desperately missing Betty Ross, the only woman he has ever loved. He is pursued by warmongers who want to use his powers for their own purposes and a nightmarish beast of pure adrenaline and aggression called the Abomination whose powers match that of the Hulk. A fight of epic proportions ensues as Bruce must call upon the hero within to rescue New York City from total destruction.