Mike Weiss is a talented young Houston lawyer and a functioning drug addict. Paul Danziger, his longtime friend and partner, is the straight-laced and responsible yin to Mike's yang. Their mom-and-pop personal injury law firm is getting by, but things really get interesting when they decide to take on a case involving Vicky, a local ER nurse, who is pricked by a contaminated needle on the job. As Weiss and Danziger dig deeper into the case, heavyweight attorneys move in on the defense.